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Antigenic Specificity | Human Thymidylate Synthetase |
Clone | [PAT1S5AT] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG2b k |
Format | Protein G purified |
Size | 0.005 mg, 0.02 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Introduction: Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate as a cofactor which maintains the dTMP (thymidine-5-prime monophosphate) pool vital for DNA replication and repair. Thymidylate synthase plays an important role as a cancer chemotherapeutic agent. Thymidylate synthase is the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and several folate analogs. |
Immunogen | Immunogen: Anti-human TYMS mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TYMS amino acids 1-313 purified from E Coli. |
Other Names | [TYMS; Thymidylate Synthetase, Mouse Human; TMS; EC 2.1.1.45; HST422; Thymidylate synthase; TSase; TS; TYMS; MGC88736], [tyms; TYSY] |
Gene, Accession # | [TYMS], Gene ID: 105019340, NCBI: NP_001291066.1 |
Catalog # | MBS140340 |
Price | $140, $205, $505 |
Order / More Info | Human Thymidylate Synthetase Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |