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Antigenic Specificity | ZBTB5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: At least two isoforms of ZBTB5 are known to exist; this antibody will recognize both isoforms. This antibody is predicted to not cross-react with other ZBTB protein family members. The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB5 was identified though sequence analysis as a POZ domain Kruppel-like zinc finger (POK) protein. Further experiments indicated that it binds DNA and can directly repress transcription of the cell cycle arrest gene p21. ZBTB5 can also interact with co-repressor histone deacetylase complexes such as BCoR, NCoR, and SMRT via its POZ domain, resulting in deacetylation of histones Ac-H3 and Ac-H4 at the proximal promoter. ZBTB5 |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 16 amino acid peptide near the carboxy terminus of human ZBTB6. |
Other Names | [Zinc finger and BTB domain-containing protein 5] |
Gene, Accession # | [ZBTB5], Gene ID: 9925, NCBI: NP_055687 |
Catalog # | MBS9411314 |
Price | $320 |
Order / More Info | ZBTB5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |