Hsp90 Complex Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Hsp90 Complex |
| Clone | [8D3] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat, rabbit |
| Isotype | IgM |
| Format | APC-Cy7 conjugate |
| Size | 0.2 mg |
| Concentration | 1 mg/ml |
| Applications | Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Detects 90 kDa. Co-immunoprecipitates HSP90 complexes, including HSP70, Hop, Ah receptors, glucocorticoid receptors, heme-regulated eukaryotic initiation factor 2alpha (eIF-2alpha) kinase (HRI). HSP90 is a highly conserved and essential stress protein that is expressed in all eukaryotic cells. From a functional perspective, HSP90 participates in the folding, assembly, maturation, and stabilization of specific proteins as an integral component of a chaperone complex (1-4). Despite its label of being a heat-shock protein, HSP90 is one of the most highly expressed proteins in unstressed cells (1-2% of cytosolic protein). It carries out a number of housekeeping functions-including controlling the activity, turnover, and trafficking of a variety |
| Immunogen | Immunogen: Ah receptor (Aryl hydrocarbon receptor) |
| Other Names | [Mouse Human HSP90 complex IgM; HSP90 complex : APC/Cy7; HSP84; HSP90; HSP90 beta; HSP90B; HSPC2; HSPCB; Heat shock protein HSP 90-beta; HSP 90; Heat shock 84 kDa; HSP 84; HSP84; HSP90AB1; HSP90B; HSPC2; HSPCB] |
| Gene, Accession # | [HSP90], Gene ID: 3326, NCBI: NP_001258898.1, UniProt: P08238 |
| Catalog # | MBS8002146 |
| Price | $740 |
| Order / More Info | Hsp90 Complex Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Arlander SJH, et al. (2003) J Biol Chem 278: 52572-52577. 2. Pearl H, et al. (2001) Adv Protein Chem 59:157-186. 3. Neckers L, et al. (2002) Trends Mol Med 8:S55-S61. 4. Pratt W, Toft D. (2003) Exp Biol Med 228:111-133. 5. Pratt W, Toft D. (1997) Endocr Rev 18: 306-360. 6. Pratt WB. (1998) Proc Soc Exptl Biol Med 217: 420-434. 7. Whitesell L, et al. (1994) Proc Natl Acad Sci USA 91: 8324-8328. 8. Perdew, G. H. (1988) JBC 263 (27): 13802-13805. 9. Dalman, F. C. et al.(1989) JBC 264(33): 19815-19821. 10. Uma, S. et al. (1997) JBC 272(17): 11648-11656. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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