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Antigenic Specificity | TNIP3 (N-term), 74-102 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This TNIP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-102 amino acids from the N-terminal region of human TNIP3. TNIP3 binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. It Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding. |
Immunogen | n/a |
Other Names | [TNFAIP3-interacting protein 3; A20-binding inhibitor of NF-kappa-B activation 3; ABIN-3; Listeria-induced gene protein; TNIP3 HGNC:19315); ABIN3; LIND] |
Gene, Accession # | [TNIP3], Gene ID: 79931, NCBI: NP_001122315.2, UniProt: Q96KP6 |
Catalog # | MBS9215153 |
Price | $165, $370 |
Order / More Info | TNIP3 (N-term), 74-102 Antibody from MYBIOSOURCE INC. |
Product Specific References | Folco, E.J., et al. J. Biol. Chem. 284(38):25569-25575(2009) Verstrepen, L., et al. Biochem. Pharmacol. 78(2):105-114(2009) Wullaert, A., et al. J. Biol. Chem. 282(1):81-90(2007) Staege, H., et al. Immunogenetics 53(2):105-113(2001) |