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Antigenic Specificity | MAP1LC3B |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MAP1LC3B antibody detects endogenous levels of total MAP1LC3B. Description: The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.Function: Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are invol |
Immunogen | Immunogen: Purified recombinant fragment of human MAP1LC3B expressed in E. Coli Subcellular Location: Cytoplasm > Cytoskeleton. Endomembrane System. Cytoplasmic Vesicle > Autophagosome Membrane. LC3-II binds to the autophagic membranes. Tissue Specificity: Most abundant in heart, brain, skeletal muscle and testis. Little expression observed in liver. |
Other Names | [ATG8F; Autophagy-related protein LC3 B; Autophagy-related ubiquitin-like modifier LC3 B; LC3B; LC3II; MAP1 light chain 3 like protein 2; MAP1 light chain 3-like protein 2; MAP1A/1BLC3; MAP1A/MAP1B LC3 B; MAP1A/MAP1B light chain 3 B; MAP1ALC3; MAP1LC3B a; Map1lc3b; Microtubule associated protein 1 light chain 3 beta; Microtubule-associated protein 1 light chain 3 beta; Microtubule-associated proteins 1A/1B light chain 3B; MLP3B_HUMAN] |
Gene, Accession # | [MAP1LC3B], Gene ID: 81631, NCBI: NP_073729.1, UniProt: Q9GZQ8 |
Catalog # | MBS9602771 |
Price | $235, $295, $370 |
Order / More Info | MAP1LC3B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |