Mouse CD119 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse CD119
Clone[GR-20]
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG2a
Formatunconjugated
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS)
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DescriptionCDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-gammaRalpha chain. It is a class II cytokine receptor family member that serves as a IFN-gamma-binding chain associated with the IFN-gamma beta chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-gamma induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-gamma initiates and regulates a variety of immune responses.
Immunogenn/a
Other Names[Mouse CD119; Interferon gamma receptor 1; Ifngr1; IFN-gamma-R1; IFN-gamma-R-alpha; CD119]
Gene, Accession #[CD119], Gene ID: 15979, NCBI: NP_034641.1, UniProt: P15261
Catalog #MBS2553979
Price$100, $115
Order / More InfoMouse CD119 Antibody from MYBIOSOURCE INC.
Product Specific References1. Basu M, et al. 1988. P. Natl. Acad. Sci. USA 85:6282. 2. Codias EK, et al. 1990. J. Immunol. 144:2197.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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