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Antigenic Specificity | MMS19 (Center), 411-437 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.35 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MMS19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 411-437 amino acids from the Central region of human MMS19. MMS19 may play a role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription by interacting with ERCC2/XPD and ERCC3/XPB helicases, both subunits of NER-transcription factor TFIIH. May also function as a transcriptional coactivator of estrogen receptor (ER). May be involved in regulation of ER activity by bridging TFIIH with ER or may facilitate TFIIH-mediated phosphorylation of ER in specific promoters and cell types. |
Immunogen | n/a |
Other Names | [MMS19 nucleotide excision repair protein homolog; hMMS19; MET18 homolog; MMS19-like protein; MMS19; MMS19L] |
Gene, Accession # | [MMS19], Gene ID: 64210, NCBI: NP_071757.4, UniProt: Q96T76 |
Catalog # | MBS9202551 |
Price | $165, $370 |
Order / More Info | MMS19 (Center), 411-437 Antibody from MYBIOSOURCE INC. |
Product Specific References | Ito, S., et al. Mol. Cell 39(4):632-640(2010) Briggs, F.B., et al. Am. J. Epidemiol. 172(2):217-224(2010) McWilliams, R.R., et al. Cancer Epidemiol. Biomarkers Prev. 18(4):1295-1302(2009) Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) : Hatfield, M.D., et al. DNA Repair (Amst.) 5(8):914-924(2006) |