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Antigenic Specificity | Human S100 PROTEIN |
Clone | [8B10] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.2 mg |
Concentration | IgG concentration 1 mg/ml |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Human S100 Protein antibody, clone 8B10 recognizes S100 protein derived from human brain tissue. It is a 21kDa acidic calcium-binding protein synthesised by astroglial cells. It can be found predominantly as two isoforms, the alpha-beta heterodimer (S100a) and the beta-beta homodimer (S100b). The S100 family of proteins have been implicated in a large variety of intracellular and extracellular regulatory activities, such as cellular energy metabolism, cytoskeleton modification, cell proliferation and differentiation. When glial cells are damaged, S100 protein is leaked into the extracellular matrix and cerebrospinal fluid, further releasing into the bloodstream. S100 protein can be used as a sensitive and reliable marker for nerv |
Immunogen | Immunogen: Human brain S100 protein Fusion Partners: Spleen cells from immunised BALB/c mice were fused with cells of the Sp2/0 myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Human |
Other Names | n/a |
Gene, Accession # | [S100] |
Catalog # | MBS214513 |
Price | $430 |
Order / More Info | Human S100 PROTEIN Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |