Human CLUSTERIN Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Human CLUSTERIN antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Human CLUSTERIN |
| Clone | [3R3/2] |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | IgG concentration 1.0 mg/ml |
| Applications | Immunohistology Frozen, ELISA (EIA), Flow cytometry (FC/FACS), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This item recognises clusterin, an ubiquitously expressed protein of two 40-kD chains, alpha and beta, covalently joined by disulfide bonds. It exists in two forms; a pro-apoptotic form localised to the nucleus and a pro-survival secreted form.. Both are thought to be involved in DNA repair and cell cycle regulation. The secreted form is thought to inhibit apoptotic signalling by BAX, Clusterin suppression can sensitise cells to chemotherapy. Clusterin is overexpressed in human prostate cancer, breast cancers and squamous cell carcinomas. . Part of the SC5b-9 complex, clusterin prevents the binding of a C5b-C7 complex to the membrane of the target cell inhibiting the complement cascade. Clusterin acts as an extracellular chaperone inhibit |
| Immunogen | Immunogen: Glomerular basement membrane from a post-mortem kidney. Histology Positive Control Tissue: Kidney from post streptocial glomerulonephritis patients. Buffer Solution: Borate buffered saline Target Species: Human |
| Other Names | [clusterin preproprotein; Clusterin; clusterin; aging-associated protein 4; apolipoprotein J; complement cytolysis inhibitor; complement lysis inhibitor; complement-associated protein SP-40,40; ku70-binding protein 1; sulfated glycoprotein 2; testosterone-repressed prostate message 2; clusterin; Aging-associated gene 4 protein; Apolipoprotein J; Apo-J; Complement cytolysis inhibitor; CLI; Complement-associated protein SP-40,40; Ku70-binding protein 1; NA1/NA2; Testosterone-repressed prostate message 2; TRPM-2], [CLU; CLU; CLI; AAG4; APOJ; CLU1; CLU2; KUB1; SGP2; APO-J; SGP-2; SP-40; TRPM2; TRPM-2; NA1/NA2; APOJ; CLI; KUB1; Apo-J; CLI; TRPM-2] |
| Gene, Accession # | Gene ID: 1191, NCBI: NP_001822.3, UniProt: P10909 |
| Catalog # | MBS212917 |
| Price | $670 |
| Order / More Info | Human CLUSTERIN Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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