Human NFkB, p65 (NF-kB, Nuclear Factor kappa B, RelA) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human NFkB, p65 (NF-kB, Nuclear Factor kappa B, RelA) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | bovine, dog, Drosophila, hamster, human, mouse, porcine, rabbit, rat, Xenopus |
| Isotype | n/a |
| Format | Protein A purified |
| Size | 0.1 mL, 0.25 mL |
| Concentration | 1mg/ml |
| Applications | ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes human NF kappa B at ~65kD. Species Crossreactivity: mouse, rat, hamster, rabbit, bovine, porcine, canine, Drosophila and Xenopus. NF kappa B is a heterodimer consisting of a 50kD DNA binding subunit and a 65kD transactivating subunit (RelA). The p50/p65 heterodime is present in the cytoplasm in inactive form bound to its inhibitor, IkB. Upon stimulation of cells with stimuli like LPS, Interleukin-1, IkB gets phosphorylated and degraded by proteosomes releasing the activated NFkB which goes to the nucleus inducing gene expression. NFkB was originally identified as transcriptional activator for kappa light cahain gene in B cells. |
| Immunogen | Immunogen: Synthetic peptide from the C-terminus of human NF kappa B protein. Cellular Localization: Cytoplasmic. |
| Other Names | [-NFkB, p65 (NF-kB, Nuclear Factor kappa B, RelA)], [NKIRAS2; NKIRAS2; KBRAS2; kappaB-Ras2; KBRAS2; Kappa B-Ras protein 2; KappaB-Ras2] |
| Gene, Accession # | Gene ID: 28511, NCBI: NP_001138401.1, UniProt: Q9NYR9 |
| Catalog # | MBS631230 |
| Price | $420, $470 |
| Order / More Info | Human NFkB, p65 (NF-kB, Nuclear Factor kappa B, RelA) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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