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Antigenic Specificity | Mouse Ntrk1 (Center) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (predicted reactivity: rat) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Mouse Ntrk1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 481-515 amino acids from the Central region of human Mouse Ntrk1. Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand, it can also bind and be activated by NTF3/neurotrophin-3. However, NTF3 only supports axonal extension through NTRK1 but has no effect on neuron survival. Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates |
Immunogen | n/a |
Other Names | [High affinity nerve growth factor receptor; Neurotrophic tyrosine kinase receptor type 1; Ntrk1] |
Gene, Accession # | [Ntrk1], Gene ID: 18211, NCBI: NP_001028296.1, UniProt: Q3UFB7 |
Catalog # | MBS9206006 |
Price | $165, $370 |
Order / More Info | Mouse Ntrk1 (Center) Antibody from MYBIOSOURCE INC. |
Product Specific References | Carninci P.,et al.Science 309:1559-1563(2005). Smeyne R.J.,et al.Nature 368:246-249(1994). Fagan A.M.,et al.J. Neurosci. 16:6208-6218(1996). Makkerh J.P.,et al.EMBO Rep. 6:936-941(2005). Lo K.Y.,et al.J. Biol. Chem. 280:41744-41752(2005). |