Mouse Ntrk1 (Center) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse Ntrk1 (Center)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse (predicted reactivity: rat)
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis Mouse Ntrk1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 481-515 amino acids from the Central region of human Mouse Ntrk1. Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand, it can also bind and be activated by NTF3/neurotrophin-3. However, NTF3 only supports axonal extension through NTRK1 but has no effect on neuron survival. Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates
Immunogenn/a
Other Names[High affinity nerve growth factor receptor; Neurotrophic tyrosine kinase receptor type 1; Ntrk1]
Gene, Accession #[Ntrk1], Gene ID: 18211, NCBI: NP_001028296.1, UniProt: Q3UFB7
Catalog #MBS9206006
Price$165, $370
Order / More InfoMouse Ntrk1 (Center) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesCarninci P.,et al.Science 309:1559-1563(2005). Smeyne R.J.,et al.Nature 368:246-249(1994). Fagan A.M.,et al.J. Neurosci. 16:6208-6218(1996). Makkerh J.P.,et al.EMBO Rep. 6:936-941(2005). Lo K.Y.,et al.J. Biol. Chem. 280:41744-41752(2005).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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