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Antigenic Specificity | Human STEM CELL FACTOR |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | ELISA (EIA), Functional Assays (FN), Immunohistology Paraffin*, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Goat anti Human Stem Cell Factor antibody recognizes human stem cell factor (SCF), a type I transmembrane protein and haematopoietic growth factor, which acts in synergy with other growth factors and signals through the c-Kit receptor. Interaction between SCF and the receptor tyrosine kinase c-Kit is an essential step for the proliferation, survival and differentiation of haematopoietic progenitor cells, mast cells, myelanocytes and germ cells, and plays an important role in follicular development. The association between SCF and c-Kit is also involved with the progression and invasiveness of tumours, and deficiencies of either SCF or c-Kit result in mast cell deficiency and macrocytic anaemia. |
Immunogen | Immunogen: Recombinant human stem cell factor. Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to human stem cell factor were raised by repeated immunisations of goats with highly purified antigen. Purified IgG prepared by affinity chromatography. Target Species: Human |
Other Names | [kit ligand isoform b; Kit ligand; kit ligand; c-Kit ligand; familial progressive hyperpigmentation 2; mast cell growth factor; steel factor; stem cell factor; KIT ligand; Mast cell growth factor; MGF; Stem cell factor; SCF; c-Kit ligandSoluble KIT ligand; sKITLG], [KITLG; KITLG; SF; MGF; SCF; FPH2; KL-1; Kitl; SHEP7; MGF; SCF; MGF; SCF; sKITLG] |
Gene, Accession # | Gene ID: 4254, NCBI: NP_000890.1, UniProt: P21583 |
Catalog # | MBS221498 |
Price | $550 |
Order / More Info | Human STEM CELL FACTOR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |