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Antigenic Specificity | HER-2 / c-erbB-2 / neu /CD340 |
Clone | [ERB2/776] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MAb is specific to c-erbB-2/HER-2 and shows minimal cross-reaction with other members of the family. C-erbB-2/HER-2 is a member of the EGFR family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary. |
Immunogen | Immunogen: Recombinant intracellular domain of human HER-2 protein |
Other Names | [p185, CD340, Verb b2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog], [ERBB2; ERBB2; NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu; HER2; MLN19; NEU; NGL; MLN 19] |
Gene, Accession # | [ERBB2], Gene ID: 2064, NCBI: NP_001005862.1, UniProt: P04626 |
Catalog # | MBS439568 |
Price | $190, $340, $340 |
Order / More Info | HER-2 / c-erbB-2 / neu /CD340 Antibody from MYBIOSOURCE INC. |
Product Specific References | Utrilla JC, et al. Histopathology. 34: 60-65 (1999). Wright C, et al. British Journal of Cancer. 65: 118-121 (1992). Corbett IP, et al. Journal of Pathology. 161: 15-25 (1990) |