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Antigenic Specificity | DOG CD44 |
Clone | [YKIX337.8.7] |
Host Species | Rat |
Reactive Species | n/a |
Isotype | IgG2a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0 mg/ml |
Applications | Immunohistology Frozen, Flow cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rat anti Dog CD44 antibody, clone YKIX337.8.7 recognises canine CD44, also known as H-CAM, a single-pass type 1 membrane of approximately 90kDa expressed by most leucocytes and epithelial cells. CD44 expression is markedly increased upon cell activation (Alldinger et al. 2000).CD44 is involved in cell-cell, cell adhesion and cell migration and is the principal cellular receptor for hyaluronate via it's LINK domain, additionally CD44 also interacts with other ligands including collagens and metalloproteinases. Studies have demonstrated that altered CD44 expression is detected in a many forms of invasive and metasic cancers, CD44 expression has been observed on canine mammary and melanocytic tumours (Serra et al. 2004). |
Immunogen | n/a |
Other Names | [CD44 antigen; CD44 antigen; CD44 antigen; ECMR-III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; PGP-1; PGP-I; extracellular matrix receptor-III; hermes antigen; hyaluronate receptor; phagocytic glycoprotein 1; phagocytic glycoprotein I; Extracellular matrix receptor-III; ECMR-III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Hermes antigen; Hyaluronate receptor; Phagocytic glycoprotein 1; PGP-1; Phagocytic glycoprotein I; PGP-I; CD_antigen: CD44], [CD44; CD44; ECMR-III; PGP-1; PGP-I] |
Gene, Accession # | [CD44], Gene ID: 403939, NCBI: Q28284.1, UniProt: Q28284 |
Catalog # | MBS224592 |
Price | $320 |
Order / More Info | DOG CD44 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |