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Antigenic Specificity | OMA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions. |
Immunogen | Immunogen: Recombinant human Metalloendopeptidase OMA1, mitochondrial protein |
Other Names | [Metalloendopeptidase OMA1; mitochondrial; Metalloprotease-related protein 1; MPRP-1; Overlapping with the m-AAA protease 1 homolog; OMA1; MPRP1] |
Gene, Accession # | [OMA1], Gene ID: 115209, NCBI: NP_660286.1, UniProt: Q96E52 |
Catalog # | MBS7000227 |
Price | $160, $235 |
Order / More Info | OMA1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |