Bid Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Bid antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Bid |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.03 mg, 0.1 mg |
| Concentration | 0.5 mg/ml |
| Applications | Western Blot (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background: Bid, a BH3 domain-containing proapoptotic Bcl-2 family member, is localized in the cytosolic fraction of cells as an inactive precursor. Its active form is generated upon proteolytic cleavage by caspase-8 in the Fas signaling pathway. Cleaved Bid translocates to mitochondria and releases its potent proapoptotic activity, which in turn induces cytochrome c release and mitochondrial damage. The cytochrome c releasing activity of Bid was antagonized by Bcl-2. Mutation in the SH3 domain can diminish the cytochrome c releasing activity. In the animal model studies, Bid-deficient mice are found resistant to the lethal effects of death factor signals relayed thromugh Fas. |
| Immunogen | Immunogen: Synthetic peptide surrounding amino acid 37 of human Bid |
| Other Names | [FP497; MGC42355; MGC15319], [BID; BID; FP497; BID] |
| Gene, Accession # | [Bid], Gene ID: 637, NCBI: NP_001187.1, UniProt: P55957 |
| Catalog # | MBS840612 |
| Price | $150, $290 |
| Order / More Info | Bid Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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