RPS3/Ribosomal Protein S3 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | RPS3/Ribosomal Protein S3 |
| Clone | monoclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.03 mg, 0.1 mg, 0.1 mg |
| Concentration | n/a |
| Applications | Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Involved in translation as a component of the 40S small ribosomal subunit (PubMed: 8706699). Has endonuclease activity and plays a role in repair of damaged DNA (PubMed: 7775413). Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA (PubMed: 15707971). Displays high binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS) (PubMed: 14706345). Has also been shown to bind with similar affinity to intact and damaged DNA (PubMed: 18610840). Stimulates the N-glycosylase activity of the base excision protein OGG1 (PubMed: 15518571). Enhances the uracil excision activity of UNG1 (PubMed: 18973764). |
| Immunogen | Immunogen: A synthesized peptide derived from human RPS3. Subcellular Localization: Cytoplasm. Nucleus. Nucleus, nucleolus. Mitochondrion inner membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton, spindle. In normal cells, located mainly in the cytoplasm with small amounts in the nucleus but translocates to the nucleus in cells undergoing apoptosis (By similarity). Nuclear translocation is induced by DNA damaging agents such as hydrogen peroxide (PubMed: 17560175). Accumulates in the |
| Other Names | [40S ribosomal protein S3; 4.2.99.18; RPS3; OK/SW-cl.26], [RPS3; RPS3; S3] |
| Gene, Accession # | [RPS3], Gene ID: 6188, NCBI: NP_000996.2, UniProt: P23396 |
| Catalog # | MBS179685 |
| Price | $160, $340, $340 |
| Order / More Info | RPS3/Ribosomal Protein S3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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