Phospho-p95/NBS1 (Ser432) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-p95/NBS1 (Ser432) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, ratpredicted: porcine, bovine, horse, sheep, dog |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-p95/NBS1 (Ser432) Antibody detects endogenous levels of p95/NBS1 only when phosphorylated at Ser432. Description: Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11. RAD50 may be required to bind DNA ends and hold them in close proximity. NBN modulate the DNA damage signal sensing by recruiting PI3/PI4-kinase family memb |
| Immunogen | Immunogen: A synthesized peptide derived from human p95/NBS1 around the phosphorylation site of Ser432. Tissue Specificity: Ubiquitous. Expressed at high levels in testis. |
| Other Names | [AT V1; AT V2; ATV; Cell cycle regulatory protein p95; FLJ10155; MGC87362; Nbn; NBN_HUMAN; NBS 1; NBS; NBS1; Nibrin; Nijmegen breakage syndrome 1 (nibrin); Nijmegen breakage syndrome; Nijmegen breakage syndrome protein 1; p95; p95 protein of the MRE11/RAD50 complex] |
| Gene, Accession # | [p95/NBS1], Gene ID: 4683, NCBI: NP_002476.2, UniProt: O60934 |
| Catalog # | MBS9610501 |
| Price | $225, $280, $340 |
| Order / More Info | Phospho-p95/NBS1 (Ser432) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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