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Antigenic Specificity | Angiopoietin 2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Angiopoietin-2(ANGPT2) detection. Tested with WB in Human. Background: Angiopoietin 1 and Angiopoietin 2 are important for development of the endothelium, by regulating tyrosine phosphorylation of the membrane receptor Tie 2. Angiopoietin 2 is only 60% homologous with Angiopoietin 1. Angiopoietin-2 is a naturally occurring antagonist of angiopoietin-1 that competes for binding to the TIE2 receptor and blocks ANGPT1-induced TIE2 autophosphorylation. Angiopoietin 1 binding to Tie 2 causes phosphorylation of the receptor. Angiopoietin 2 competes for this binding, and thus blocks receptor phosphorylation. Angiopoietin 2 expression occurs at sites of vascular remodelling: dorsal aorta and major aor |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Angiopoietin 2 (454-468aa NLNGMYYPQRQNTNK). |
Other Names | [Angiopoietin-2(ANG-2); angiopoietin 2; AGPT 2; Agpt2; ANG 2; ANG-2; ANG2; Angiopoietin 2a; Angiopoietin 2B; Angiopoietin-2; Angiopoietin2; ANGP2_HUMAN; ANGPT 2; ANGPT2; ANGPT-2; Tie2 ligand], [ANGPT2; ANGPT2; ANG2; AGPT2; ANG-2] |
Gene, Accession # | [ANGPT2], Gene ID: 285, NCBI: O15123.1, UniProt: O15123 |
Catalog # | MBS175128 |
Price | $280 |
Order / More Info | Angiopoietin 2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |