ATM (C-term) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | ATM (C-term) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human; predicted reactivity: mouse |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.08 mL, 0.4 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This ATM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3027~3056 amino acids from the C-terminal region of human ATM. Description: ATM is involved in signal transduction, cell cycle control and DNA repair, and may function as a tumor suppressor. It is necessary for activation of ABL1 and SAPK, and phosphorylates p53, NFKBIA, BRCA1, CTIP, NIBRIN (NBS1), TERF1, and RAD9. This protein has potential roles in vesicle and/or protein transport, T-cell development, gonad and neurological function. ATM is also part of the BRCA1-associated genome surveillance complex. ATM is induced by ionizing radiation. Defects in ATM are the cause of ataxia talangiectasia (AT), also known as Louis-Bar syndrome, a rare |
| Immunogen | n/a |
| Other Names | [Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated; ATM] |
| Gene, Accession # | [ATM], Gene ID: 472, NCBI: NP_000042.3, UniProt: Q13315 |
| Catalog # | MBS9217164 |
| Price | $165, $370 |
| Order / More Info | ATM (C-term) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Suzuki, A., et al., J. Biol. Chem. 278 (1):48-53 (2003). Kishi, S., et al., J. Biol. Chem. 276 (31):29282-29291 (2001). Schaffner, C., et al., Proc. Natl. Acad. Sci. U.S.A. 97 (6):2773-2778 (2000). Gatei, M., et al., Nat. Genet. 25 (1):115-119 (2000). Becker-Catania, S.G., et al., Mol. Genet. Metab. 70 (2):122-133 (2000). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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