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Antigenic Specificity | RAT CD252 |
Clone | [ATM-2] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | Flow cytometry (FC/FACS)* |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Rat CD252 antibody, clone ATM-2 specifically recognizes rat CD252, otherwise known as OX40L or CD134L, a 22kDa type II transmembrane glycoprotein and member of the TNF superfamily, expressed by antigen-presenting cells including activated dendritic cells and B cells, and also by vascular endothelium. The interaction of CD252 with its receptor OX40/CD134, acts as a co-stimulator of T cell activation, proliferation and both Th1 and Th2 cytokine production, and is also important in activated B cell proliferation and secretion of immunoglobulins (Igs). CD252/OX40 interaction has been implicated in HTLV-1 associated diseases including myelopathy and adult T cell leukaemia, and also with the autoimmune diseases rheumatoid arthritis and |
Immunogen | Immunogen: ACI-S1 rat T-cell lymphoma cell line. Buffer Solution: Phosphate buffered saline Target Species: Rat |
Other Names | [tumor necrosis factor ligand superfamily member 4; Tumor necrosis factor ligand superfamily member 4; tumor necrosis factor ligand superfamily member 4; OX40 ligand; tumor necrosis factor (ligand) superfamily, member 4; OX40 ligand; OX40L; CD_antigen: CD252], [Tnfsf4; Tnfsf4; Ox40l; Ox40l; Txgp1; OX40L] |
Gene, Accession # | [CD252], Gene ID: 89814, NCBI: NP_446004.1, UniProt: Q9Z2P3 |
Catalog # | MBS219527 |
Price | $300 |
Order / More Info | RAT CD252 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |