Phospho-CRK (S41) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-CRK (S41) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: mouse, rat) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.445 |
| Applications | Dot Blot (DB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This CRK Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S41 of human CRK. CRK is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. It has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. |
| Immunogen | n/a |
| Other Names | [Adapter molecule crk; Proto-oncogene c-Crk; p38; CRK] |
| Gene, Accession # | [CRK], Gene ID: 1398, NCBI: NP_005197.3, UniProt: P46108 |
| Catalog # | MBS9205937 |
| Price | $165, $370 |
| Order / More Info | Phospho-CRK (S41) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Bougneres, L., et al., J. Cell Biol. 166(2):225-235 (2004). Stoletov, K.V., et al., Exp. Cell Res. 295(1):258-268 (2004). Miller, C.T., et al., Oncogene 22(39):7950-7957 (2003). Sun, J., et al., J. Biol. Chem. 278(35):32794-32800 (2003). Zhang, X.A., et al., J. Biol. Chem. 278(29):27319-27328 (2003). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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