IRS-1 Inhibition Antibody Sampler Kit Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | IRS-1 Inhibition Antibody Sampler Kit |
| Clone | n/a |
| Host Species | n/a |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | unconjugated |
| Size | 1 kit |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background: Insulin receptor substrate 1 (IRS-1) is one of the major substrates of the insulin receptor kinase. IRS-1 contains multiple tyrosine phosphorylation motifs that serve as docking sites for SH2-domain containing proteins that mediate the metabolic and growth-promoting functions of insulin. IRS-1 also contains over 30 potential serine/threonine phosphorylation sites, many of which are related to negative feedback loops activated during insulin signaling. Ser307 (mouse Ser302) of IRS-1 is regulated by FOX01, IKKgamma, and MYO1C. Ser312 (mouse Ser307) of IRS-1 is phosphorylated by JNK and IKK. PKC phosphorylates mouse IRS-1 at Ser323 (mouse Ser318) by insulin receptor activation or by other stimulation such as TPA, IL-6, and retinoic |
| Immunogen | n/a |
| Other Names | n/a |
| Gene, Accession # | [IRS-1] |
| Catalog # | MBS2550093 |
| Price | $395 |
| Order / More Info | IRS-1 Inhibition Antibody Sampler Kit Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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