Mouse Brd7 (Center) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse Brd7 (Center) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This MOUSE Brd7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 387-418 amino acids from the Central region of human MOUSE Brd7. Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Transcriptional corepressor that down-regulates the expression of target genes. Binds to target promoters, leading to increased histone H3 acetylation at 'Lys-9' (H3K9ac). Binds to the ESR1 promoter. Recruits BRCA1 and POU2F1 to the ESR1 promoter. Coactivator for TP53-mediated activation of transcription of a set of target genes. Required for TP53-mediated cell-cycle arrest in response to oncogene activation. Promotes acetylation of TP53 at 'Lys-382', and thereby promotes efficient re |
| Immunogen | n/a |
| Other Names | [Bromodomain-containing protein 7; 75 kDa bromodomain protein; Brd7; Bp75] |
| Gene, Accession # | [Brd7], Gene ID: 26992, NCBI: NP_036177.1, UniProt: O88665 |
| Catalog # | MBS9204705 |
| Price | $165, $370 |
| Order / More Info | Mouse Brd7 (Center) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Cuppen E.,et al.FEBS Lett. 459:291-298(1999). Carninci P.,et al.Science 309:1559-1563(2005). Kim S.,et al.Cancer Res. 63:4792-4795(2003). Kaeser M.D.,et al.J. Biol. Chem. 283:32254-32263(2008). Kikuchi M.,et al.Biochim. Biophys. Acta 1793:1828-1836(2009). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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