B-raf Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityB-raf
Clonepolyclonal
Host SpeciesChicken
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionB-raf Antibody: B-raf belongs to the raf/mil family of serine/threonine protein kinases and plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. The Ras/Raf/MEK/ERK and Ras/PI3K/PTEN/Akt pathways interact with each other to regulate growth and in some cases tumorigenesis. Mutations in B-raf have been associated with several cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung, leading to speculation on the possibility of B-raf as a therapeutic target for treating cancers. Mutations in this gene have also been associated with cardiofaciocutaneous syndrome (CFCS), a d
ImmunogenImmunogen: B-raf antibody was raised against an 18 amino acid synthetic peptide near the center of human B-raf. Buffer: B-raf Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[B-raf; NS7; BRAF1; RAFB1; B-RAF1; Proto-oncogene B-Raf; v-raf murine sarcoma viral oncogene homolog B1], [BRAF; BRAF; NS7; BRAF1; RAFB1; B-RAF1; BRAF1; RAFB1]
Gene, Accession #[BRAF], Gene ID: 673, NCBI: P15056.4, UniProt: P15056
Catalog #MBS151403
Price$375
Order / More InfoB-raf Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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