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Antigenic Specificity | LMNA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total LMNA protein. Lamins are nuclear membrane structural components that are important in maintaining normal cell functions such as cell cycle control, DNA replication, and chromatin organization (1-3). Lamin A/C is cleaved by caspase-6 and serves as a marker for caspase-6 activation. During apoptosis, lamin A/C is specifically cleaved into a large (41-50 kDa) and a small (28 kDa) fragment (3,4). The cleavage of lamins results in nuclear disregulation and cell death (5,6). |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human LMNA. |
Other Names | [LMNA; CDCD1; CDDC; CMD1A; CMT2B1] |
Gene, Accession # | [LMNA], Gene ID: 4000, NCBI: NP_001244303.1, UniProt: P02545 |
Catalog # | MBS9414323 |
Price | $255 |
Order / More Info | LMNA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |