OCT-4 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | OCT-4 |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of OCT4. Oct-4 (POU5F1) is a transcription factor expressed in the totipotent and pluripotent stem cells of the pregastrulation embryo. It is also expressed in primordial germ cells and in the female germ line. OCT4 binds to the octamer motif (5'-ATTTGCAT-3') and forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. It is critical for early embryogenesis and for embryonic stem cell pluripotency. |
| Immunogen | n/a |
| Other Names | [POU domain, class 5, transcription factor 1 isoform 3; POU domain, class 5, transcription factor 1; POU domain, class 5, transcription factor 1; POU class 5 homeobox 1; Octamer-binding protein 3; Oct-3; Octamer-binding protein 4; Oct-4; Octamer-binding transcription factor 3; OTF-3], [POU5F1; POU5F1; OCT3; OCT4; OTF3; OTF4; OTF-3; Oct-3; Oct-4; OCT3; OCT4; OTF3; Oct-3; Oct-4; OTF-3] |
| Gene, Accession # | [OCT-4], Gene ID: 5460, NCBI: NP_001272916.1, UniProt: Q01860 |
| Catalog # | MBS857314 |
| Price | $280 |
| Order / More Info | OCT-4 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 1998. WWP2 promotes degradation of transcription factor OCT4 in human embryonic stem cells.Xu H., Wang W., Li C., Yu H., Yang A., Wang B., Jin Y.Cell Res. 19:561-573(2009). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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