AREG Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAREG
Clone[1A1G9]
Host SpeciesMouse
Reactive Specieshuman, rat
IsotypeIgG1
FormatProtein A purified
Size0.06 mL, 0.12 mL, 0.2 mL
Concentration1mg/mL
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
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DescriptionAmphiregulin (AREG) is one of the ligands of the epidermal growth factor receptor (EGFR). AREG plays a central role in mammary gland development and branching morphogenesis in organs and is expressed both in physiological and in cancerous tissues. The AREG protein is synthesized as a 252-amino acid transmembrane precursor, pro-AREG. At the plasma membrane, pro-AREG is subjected to sequential proteolytic cleavages within its ectodomain and is then released as the soluble AREG protein. Depending on the cell type and microenvironment, AREG can be produced in multiple cellular and mature forms using alternative pro-AREG cleavage sites and glycosylation motifs. Post-translastional modfications of 50-kDa pro-AREG produces a major soluble 43-kDa f
ImmunogenImmunogen: Fusion protein of Amphiregulin
Other Names[A REG; Amphiregulin; Amphiregulin B; AR; AREG; AREG; AREGB; Colorectum cell derived growth factor; Colorectum cell-derived growth factor; CRDGF; MGC13647; Schwannoma derived growth factor; SDGF]
Gene, Accession #[AREG], Gene ID: 374, NCBI: NP_001648.1, UniProt: P15514
Catalog #MBS2549035
Price$220, $290, $435
Order / More InfoAREG Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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