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Antigenic Specificity | MAP2K6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. With MAP3K3/MKK3, catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinases p38 MAPK11, MAPK12, MAPK13 and MAPK14 and plays an important role in the regulation of cellular responses to cytokines and all kinds of stresses. Especially, MAP2K3/MKK3 and MAP2K6/MKK6 are both essential for the activation of MAPK11 and MAPK13 induced by environmental stress, whereas MAP2K6/MKK6 is the major MAPK11 activator in response to TNF. MAP2K6/MKK6 also phosphorylates and activates PAK6. The p38 MAP kinase signal transduction pathway leads to direct activation of transcription factors. Nuclear targets o |
Immunogen | Immunogen: Recombinant human Dual specificity mitogen-activated protein kinase kinase 6 protein(1-334AA) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-1992 / sc-1991 / sc-6073 |
Other Names | [Dual specificity mitogen-activated protein kinase kinase 6; MAP kinase kinase 6; MAPKK 6; MAPK/ERK kinase 6; MEK 6; Stress-activated protein kinase kinase 3; SAPK kinase 3; SAPKK-3; SAPKK3; MAP2K6; MEK6; MKK6; PRKMK6; SKK3], [MAP2K6; MAP2K6; MEK6; MKK6; MAPKK6; PRKMK6; SAPKK3; SAPKK-3; MEK6; MKK6; PRKMK6; SKK3; MAP kinase kinase 6; MAPKK 6; MEK 6; SAPK kinase 3; SAPKK-3; SAPKK3] |
Gene, Accession # | [MAP2K6], Gene ID: 5608, NCBI: NP_002749.2, UniProt: P52564 |
Catalog # | MBS1493259 |
Price | $160, $235 |
Order / More Info | MAP2K6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |