Shank2, 84-309 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Shank2, 84-309 |
| Clone | [S23b-6] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Immunoblot; Immunohistochemistry; Immunocytochemistry; Immunofluorescence |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Shank2. This antibody recognizes human, mouse (weak), and rat Shank2. It does not crossreact with Shank1 or Shank3. Shank proteins are a family of scaffold proteins identified through their interaction with a variety of membrane and cytoplasmic proteins. Shank proteins at postsynaptic sites of excitatory synapses play roles in signal transmission into the postsynaptic neuron. Shank proteins are crucial in receptor tyrosine kinase signaling. Shank2 is expressed in neurons of the developing retina and could play a role in neuronal differentiation of the developing retina. Recent studies suggest that disruption of glutamate receptors at the Shank-postsynaptic platform could contribute to the destruction of post-synaptic density wh |
| Immunogen | Antigen: Fusion protein corresponding to aa 84-309 (SH3/PDZ domains) of rat Shank2 (accession no. Q9QX74). This sequence is 94% homologous with human and 97% homologous with mouse Shank2. |
| Other Names | [SH3 and multiple ankyrin repeat domains protein 2 isoform 2; SHANK2 protein; SH3 and multiple ankyrin repeat domains protein 2; OTTHUMP00000165931; OTTHUMP00000165995; OTTHUMP00000165996; OTTHUMP00000166023; OTTHUMP00000166026; OTTHUMP00000202300; cortactin-binding protein 1; GKAP/SAPAP interacting protein; cortactin SH3 domain-binding protein; proline-rich synapse associated protein 1; proline-rich synapse-associated protein 1; SH3 and multiple ankyrin repeat domains 2], [SHANK2; SHANK2; SHANK; AUTS17; CORTBP1; CTTNBP1; ProSAP1; SPANK-3] |
| Gene, Accession # | Gene ID: 22941, NCBI: NP_573573.2, UniProt: Q24JS4 |
| Catalog # | MBS190606 |
| Price | $410 |
| Order / More Info | Shank2, 84-309 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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