RPS6KA4 (C-term) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRPS6KA4 (C-term)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis RPS6KA4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 692-725 amino acids from the C-terminal region of human RPS6KA4. Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factor RELA, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin. Plays an essential role in the control of RELA transcriptional activity in response to TNF. Phosphorylates 'Ser
Immunogenn/a
Other Names[Ribosomal protein S6 kinase alpha-4; S6K-alpha-4; 90 kDa ribosomal protein S6 kinase 4; Nuclear mitogen- and stress-activated protein kinase 2; Ribosomal protein kinase B; RSKB; RPS6KA4; MSK2]
Gene, Accession #[RPS6KA4], Gene ID: 8986, NCBI: NP_001006945.1, UniProt: O75676
Catalog #MBS9209337
Price$165, $370
Order / More InfoRPS6KA4 (C-term) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesPierrat B.,et al.J. Biol. Chem. 273:29661-29671(1998). Ota T.,et al.Nat. Genet. 36:40-45(2004). Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases. Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. Deak M.,et al.EMBO J. 17:4426-4441(1998).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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