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Antigenic Specificity | Human MBL |
Clone | [4J25] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Neutr |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Human mannose/mannan-binding lectin (MBLI3/4 also MBPC) is a 25 kDa member of the collectin family of pattern-recognition molecules. It is a secreted glycoprotein that is synthesized as a 248 amino acid (aa) precursor that contains a 20 aa signal sequence, a 21 aa cysteinerich region (with three cysteines) a 58 aa collagenlike segment and a 111 aa Ctype lectin domain that binds to neutral bacterial carbohydrates. The molecule is O glycosylatedand contains multiplehydroxylated prolines and lysines. Functionally, the molecule operates as a multimer/oligomer. The basic structural unit is a homotrimer. The homotrimer iscreated by the formation of interchain disulfide bonds among the cysteinerichregions, plus a helical interaction of the collagen- |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of MBL. |
Other Names | [MBL2; MBL; MBP; MBP1; MBL2D; MBP-C; COLEC1; HSMBPC], [MBL2; MBL2; MBL; MBP; MBP1; MBPD; MBL2D; MBP-C; COLEC1; HSMBPC; COLEC1; MBL; MBP-C] |
Gene, Accession # | [MBL], Gene ID: 4153, NCBI: NP_000233.1, UniProt: P11226 |
Catalog # | MBS690857 |
Price | $490 |
Order / More Info | Human MBL Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |