Probable aconitate hydratase, mitochondrial, Ant Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Probable aconitate hydratase, mitochondrial, Ant |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG |
| Format | unconjugated |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' (H3K4me3) and monomethylated H3 'Lys-4' (H3K4me1) residues, while it has weaker activity for dimethylated H3 'Lys-36' (H3K36me2). Also catalyzes the hydroxylation of 60S ribosomal protein L8 on 'His-216'. Acts as a regulator of osteoblast differentiation via its interaction with SP7, OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7, OSX-mediated promoter activation (By similarity). May also play a role in ribosome biogenesis and in the replication or |
| Immunogen | Source Note: This monoclonal antibody is produced by immunizing mice with a polypeptide corresponding to probable aconitate hydratase, mitochondrial protein. |
| Other Names | [Probable aconitate hydratase Mouse mAb], [acnA; Aconitase] |
| Gene, Accession # | NCBI: CAL94150.1, UniProt: A1K5P5 |
| Catalog # | MBS435428 |
| Price | $440 |
| Order / More Info | Probable aconitate hydratase, mitochondrial, Ant Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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