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Antigenic Specificity | IRF4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total IRF4 protein. Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes By similarity.Grossman A., Genomics 37:229-233(1996).Iida S., Nat. Genet. 17:226-230(1997).Mungall A.J., Natur |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human IRF4. |
Other Names | [interferon regulatory factor 4; LSIRF; lymphocyte-specific interferon regulatory factor; multiple myeloma oncogene 1; MUM1] |
Gene, Accession # | [IRF4], Gene ID: 3662, NCBI: NP_001182215.1, UniProt: Q15306 |
Catalog # | MBS9408273 |
Price | $200, $255 |
Order / More Info | IRF4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |