Casp3 - middle region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCasp3 - middle region
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciescow, dog, goat, guinea pig, horse, human, porcine, rat, sheep
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis is a rabbit polyclonal antibody against Casp3. It was validated on Western BlotTarget Description: Casp3 is involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond, cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain, cleaves and activates caspase-6, -7 and -9, triggers cell adhesion in sympathetic neurons through RET cleavage, cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes.
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the middle region of Mouse Casp3
Other Names[caspase-3; Caspase-3; caspase-3; caspase 3; Apopain; Cysteine protease CPP32; CPP-32]
Gene, Accession #[CASP3], Gene ID: 12367, NCBI: NP_033940, UniProt: P70677
Catalog #MBS3215043
Price$335
Order / More InfoCasp3 - middle region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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