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Antigenic Specificity | Phospho-EIF4E (S209) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.47 |
Applications | Dot Blot (DB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Phospho-EIF4E-S209 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S209 of human EIF4E. eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G1/EIF4G3. EIF4E is also known to interact with other partners. The interaction with EIF4ENIF1 mediates the import into the nucleus. Nonphosphorylated EIF4EBP1, EIF4EBP2 and EIF4EBP3 compete with EIF4G1/EIF4G3 to interact with EIF4E; insulin stimulated MAP-kinase (MAPK1 and MAPK3) phosphorylation of EIF4EBP1 causes dissociation of the complex allowing EIF4G1/EIF4G3 to bind and consequent initia |
Immunogen | n/a |
Other Names | [Eukaryotic translation initiation factor 4E; eIF-4E; eIF4E; eIF-4F 25 kDa subunit; mRNA cap-binding protein; EIF4E; EIF4EL1; EIF4F] |
Gene, Accession # | [EIF4E], Gene ID: 1977, NCBI: NP_001124150.1, UniProt: P06730 |
Catalog # | MBS9212456 |
Price | $165, $370 |
Order / More Info | Phospho-EIF4E (S209) Antibody from MYBIOSOURCE INC. |
Product Specific References | Rychlik,W., J. Biol. Chem. 262 (22), 10434-10437 (1987) Dorfman,J., Genomics 9 (4), 785-788 (1991) Pelletier,J., Genomics 10 (4), 1079-1082 (1991) Whalen,S.G., J. Biol. Chem. 271 (20), 11831-11837 (1996) |