VASP Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityVASP
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin
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DescriptionRabbit IgG polyclonal antibody for Vasodilator-stimulated phosphoprotein(VASP) detection. Background: Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that r
ImmunogenImmunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human VASP (78-114aa NFHQWRDARQVWGLNFGSKEDAAQFAAGMASALEALE), different from the related mouse sequence by four amino acids.
Other Names[VASP; P50552; Vasodilator-stimulated phosphoprotein], [VASP; VASP; VASP]
Gene, Accession #[VASP], Gene ID: 7408, NCBI: NP_003361.1, UniProt: P50552
Catalog #MBS178599
Price$315
Order / More InfoVASP Antibody from MYBIOSOURCE INC.
Product Specific References1. Zimmer M, Fink T, Fischer L, Hauser W, Scherer K, Lichter P, Walter U (January 1997). Cloning of the VASP (vasodilator-stimulated phosphoprotein) genes in human and mouse: structure, sequence, and chromosomal localization. Genomics. 36 (2): 227-33.2. Harbeck, B; Huttelmaier S; Schluter K; Jockusch B M; Illenberger S (October 2000). Phosphorylation of the vasodilator-stimulated phosphoprotein regulates its interaction with actin. J. Biol. Chem. UNITED STATES.275 (40): 30817-25.3. Reinhard, M; Giehl K; Abel K; Haffner C; Jarchau T; Hoppe V; Jockusch B M; Walter U (April 1995). The proline-rich focal adhesion and microfilament protein VASP is a ligand for profilins. EMBO J. ENGLAND.14 (8): 1583-9.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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