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Antigenic Specificity | KPNA5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, bovine, horse, sheep, rabbit, dog |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: KPNA5 Antibody detects endogenous levels of KPNA5. Description: Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directi |
Immunogen | Immunogen: A synthesized peptide derived from human KPNA5. Tissue Specificity: Testis. |
Other Names | [IMA5_HUMAN; Importin alpha 6; Importin subunit alpha 6; Importin subunit alpha-6; IPOA 6; IPOA6; Karyopherin alpha 5; Karyopherin alpha 5 importin alpha 6; Karyopherin subunit alpha 5; Karyopherin subunit alpha-5; KPNA 5; KPNA5; SRP 6; SRP6] |
Gene, Accession # | [KPNA5], Gene ID: 3841, NCBI: O15131.2, UniProt: O15131 |
Catalog # | MBS9611401 |
Price | $240, $280 |
Order / More Info | KPNA5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |