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Antigenic Specificity | FAF1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: FAF1 antibody detects endogenous levels of total FAF1. Function: Ubiquitin-binding protein (PubMed:19722279). Required for the progression of DNA replication forks by targeting DNA replication licensing factor CDT1 for degradation (PubMed:26842564). Potentiates but cannot initiate FAS-induced apoptosis (By similarity).Subunit Structure: Interacts with CDT1 and ATPase VCP/p97 (PubMed:26842564). Interacts (via UBA domain) with FAS (via death domain) (PubMed:10462485). Interacts (via UBA domain) with NLRP12 (via DAPIN/PYRIN domain) (PubMed:21978668). |
Immunogen | Immunogen: A synthesized peptide derived from human FAF1 Subcellular Location: Nucleus. Tissue Specificity: Most abundant in testis, slightly less abundant in skeletal muscle and heart, followed by prostate, thymus, ovary, small intestine, and colon. Not detected in the peripheral blood leukocytes. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Chicken Similarity: Pig (100%), Zebrafish (100%), Bovine (91%), Horse (100%), Sheep (100%), Dog (100%), Chicken (80%) |
Other Names | [CGI 03; FAF1; FAF1 protein; FAF1_HUMAN; Fas (TNFRSF6) associated factor 1; FAS associated factor 1; Fas associated protein factor 1; FAS-associated factor 1; FLJ37524; hFAF1; HFAF1s; Protein FAF1; TNFRSF6 associated factor 1; UBX domain protein 3A; UBX domain-containing protein 12; UBX domain-containing protein 3A; UBXD12; UBXN3A] |
Gene, Accession # | [FAF1], Gene ID: 11124, NCBI: NP_008982.1, UniProt: Q9UNN5 |
Catalog # | MBS9608972 |
Price | $240, $280 |
Order / More Info | FAF1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |