MINK1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | MINK1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: MINK1 antibody detects endogenous levels of total MINK1. Function: Serine/threonine kinase which acts as a negative regulator of Ras-related Rap2-mediated signal transduction to control neuronal structure and AMPA receptor trafficking. Required for normal synaptic density, dendrite complexity, as well as surface AMPA receptor expression in hippocampal neurons. Can activate the JNK and MAPK14/p38 pathways and mediates stimulation of the stress-activated protein kinase MAPK14/p38 MAPK downstream of the Raf/ERK pathway. Phosphorylates: TANC1 upon stimulation by RAP2A, MBP and SMAD1. Has an essential function in negative selection of thymocytes, perhaps by coupling NCK1 to activation of JNK1.Subunit Structure: Interacts with TA |
| Immunogen | Immunogen: A synthesized peptide derived from human MINK1 Subcellular Location: Cytoplasm. Cell Junction; Synapse; Postsynaptic Cell Membrane; Postsynaptic Density. Cell Projection; Axon. Cell Projection; Dendrite. Isoform 4: Golgi apparatus Tissue Specificity: Expressed in the brain, isoform 2 is more abundant than isoform 1. Isoform 3 is ubiquitously expressed. Isoform 1 is most abundant in the skeletal muscle. Isoform 4 is ubiquitously expressed with relative high levels in brain, skeletal mu |
| Other Names | [B55; GCK family kinase MiNK; hMINK; Map4k6; MAPK/ERK kinase kinase kinase 6; MEK (MAP/ERK) kinase kinase 6; MEK kinase kinase 6; MEKKK6; MGC21111; MINK 1; MINK; MINK1; Misshapen like kinase 1; Misshapen NIKs Related kinase; Misshapen/NIK related kinase; Mitogen activated protein kinase kinase kinase kinase 6; RP23-122P1.6; Ysk2; ZC3] |
| Gene, Accession # | [MINK1], Gene ID: 50488, NCBI: NP_001020108.1, UniProt: Q8N4C8 |
| Catalog # | MBS9602155 |
| Price | $240, $280 |
| Order / More Info | MINK1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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