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Antigenic Specificity | ALR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ALR antibody detects endogenous levels of ALR. Function: Isoform 1: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen.Subunit Structure: Homodimer; disulfide-linked. May form heterodimers of isoform 1 and isoform 2 (PubMed:12180965, PubMed:20593814, PubMed:21383138, PubMed:22224850). Interacts with C |
Immunogen | Immunogen: A synthesized peptide derived from human ALR. Subcellular Location: Mitochondrion Intermembrane Space and Cytoplasm. Secreted. Tissue Specificity: Ubiquitously expressed. Highest expression in the testis and liver and low expression in the muscle. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Dog, Chicken, Xenopus Similarity: Pig (100%), Zebrafish (100%), Bovine (100%), Horse (100%), Dog (100%), Chicken (100%), Xenopus (91%) |
Other Names | [ALR_HUMAN; Augmenter of liver regeneration; ERV1; ERV1 homolog; Erv1 like growth factor; FAD-linked sulfhydryl oxidase ALR; GFER; Growth factor augmenter of liver regeneration; Growth factor erv1 like; Hepatic regenerative stimulation substance; Hepatopoietin; Hepatopoietin protein; hERV1; HPO; HPO1; HPO2; HSS] |
Gene, Accession # | [ALR], Gene ID: 2671, NCBI: NP_005253.3, UniProt: P55789 |
Catalog # | MBS9603338 |
Price | $240, $280 |
Order / More Info | ALR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |