ALR Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityALR
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionSpecificity: ALR antibody detects endogenous levels of ALR. Function: Isoform 1: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen.Subunit Structure: Homodimer; disulfide-linked. May form heterodimers of isoform 1 and isoform 2 (PubMed:12180965, PubMed:20593814, PubMed:21383138, PubMed:22224850). Interacts with C
ImmunogenImmunogen: A synthesized peptide derived from human ALR. Subcellular Location: Mitochondrion Intermembrane Space and Cytoplasm. Secreted. Tissue Specificity: Ubiquitously expressed. Highest expression in the testis and liver and low expression in the muscle. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Dog, Chicken, Xenopus Similarity: Pig (100%), Zebrafish (100%), Bovine (100%), Horse (100%), Dog (100%), Chicken (100%), Xenopus (91%)
Other Names[ALR_HUMAN; Augmenter of liver regeneration; ERV1; ERV1 homolog; Erv1 like growth factor; FAD-linked sulfhydryl oxidase ALR; GFER; Growth factor augmenter of liver regeneration; Growth factor erv1 like; Hepatic regenerative stimulation substance; Hepatopoietin; Hepatopoietin protein; hERV1; HPO; HPO1; HPO2; HSS]
Gene, Accession #[ALR], Gene ID: 2671, NCBI: NP_005253.3, UniProt: P55789
Catalog #MBS9603338
Price$240, $280
Order / More InfoALR Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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