TRPC4AP (N-term), 49-75 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTRPC4AP (N-term), 49-75
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis TRPC4AP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-75 amino acids from the N-terminal region of human TRPC4AP. Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1.
Immunogenn/a
Other Names[Short transient receptor potential channel 4-associated protein; Trp4-associated protein; Trpc4-associated protein; Protein TAP1; TNF-receptor ubiquitous scaffolding/signaling protein; Protein TRUSS; TRPC4AP; C20orf188; TRRP4AP]
Gene, Accession #[TRPC4AP], Gene ID: 26133, NCBI: NP_056453.1, UniProt: Q8TEL6
Catalog #MBS9205450
Price$165, $370
Order / More InfoTRPC4AP (N-term), 49-75 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesMace, K.E., et al. J. Cell. Physiol. 225(2):444-453(2010) Choi, S.H., et al. Genes Dev. 24(12):1236-1241(2010) Poduslo, S.E., et al. Neurosci. Lett. 450(3):344-346(2009) Poduslo, S.E., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (1), 50-55 (2009) : Tsang, H.T., et al. Genomics 88(3):333-346(2006)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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