Human vitronectin receptor (CD51) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman vitronectin receptor (CD51)
Clone[NKI-M9 (former PAF2a]
Host SpeciesMouse (Balb/c)
Reactive Specieshuman
IsotypeIgG2a
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsImmunofluorescence (IF), Immunohistochemistry (IHC) (frozen), Immunoprecipitation (IP)
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DescriptionSpecificity: NKI-M9 is directed anti the CD51 antigen, alpha chain of vitronectin receptor (VNR-a chain) which forms a complex with: CD61 antigen (GP IIIa or b3 chain); b5 Integrin and b1 Integrin. The platelet a-b3 complex functions as a vitronectin receptor and platelet adhesion to vitronectin is inhibited by NKI-M9. CD51 (Cluster of Differentiation 51), known as vitronectin receptor alpha chain, or integrin alphaV is a type I integral membrane glycoprotein. CD51 forms a heterodimer with integrin beta1 (CD29), beta3 (CD61), beta5, beta6, or beta8. CD51 contains two disulfide-linked subunits of 125 kD and 24 kD. Many extracellular matrix proteins with RGD-motifs are CD51 ligands. In association with its beta chains, CD51 binds vitronectin,
ImmunogenSource Note: NKI-M9 is a Mouse monoclonal IgG2a antibody derived by fusion of SP2/0 Mouse myeloma cells with spleen cells from a BALB/c Mouse immunized with cultured melanoma cells derived from a Human melanoma metastasis.
Other Namesn/a
Gene, Accession #n/a
Catalog #MBS570190
Price$415
Order / More InfoHuman vitronectin receptor (CD51) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesNesbitt, S., et al., 1993. J. Biol. Chem. 268:16737. Zola, H., et al., 2007. Leukocyte and Stromal Cell Molecules: The CD Markers Wiley-Liss A John Wiley & Sons, Inc., PubliCation J.M.W. Quinn, N.A. Athanasou, and J.O'D McGee,1991. Histochemistry, 96:169-176
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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