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Antigenic Specificity | SH2D2A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: SH2D2A antibody detects endogenous levels of total SH2D2A. Function: Could be a T-cell-specific adapter protein involved in the control of T-cell activation. May play a role in the CD4-p56-LCK-dependent signal transduction pathway. Could also play an important role in normal and pathological angiogenesis. Could be an adapter protein that facilitates and regulates interaction of KDR with effector proteins important to endothelial cell survival and proliferation.Subunit Structure: Interacts with KDR. Interacts with TXK and ITK (By similarity).Post-translational Modifications: Phosphorylated on tyrosine residues. |
Immunogen | Immunogen: A synthesized peptide Tissue Specificity: Expression limited to tissues of the immune system and, in particular, activated T-cells. Expressed in peripheral blood leukocytes, thymus and spleen. Much lower expression or undetectable, in brain, placenta, skeletal muscle, prostate, testis, ovary, small intestine, and colon. Expressed at low levels in unstimulated T-cells, but not expressed in normal resting or activated B-cells. According to PubMed:10692392, expression is not restricted t |
Other Names | [F2771; SCAP; SH2 domain containing adapter protein; SH2 domain containing protein 2A; SH2 domain protein 2A; SH2 domain-containing adapter protein; SH2 domain-containing protein 2A; SH22A_HUMAN; Sh2d2a; T cell specific adapter protein; T cell specific adapter protein TSAd; T cell specific adpater protein TSAd; T cell-specific adapter protein; T lymphocyte specific adaptor protein; TSAd; VEGF receptor associated protein; VEGF receptor-associated protein; VRAP] |
Gene, Accession # | [SH2D2A], Gene ID: 9047, NCBI: NP_001154914.1, UniProt: Q9NP31 |
Catalog # | MBS9605951 |
Price | $240, $280 |
Order / More Info | SH2D2A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |