DFF45 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | DFF45 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | DEAE purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | DFF45 Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. A human 45 kDa DNA fragmentation factor (DFF45) was identified recently that was cleaved by caspase-3 during apoptosis. Mouse homologue of human DFF45 was identified as a DNase inhibitor designated ICAD. DFF45/ICAD have short forms that were termed DFF35 and ICADs, respectively. Upon cleavage of DFF45/ICAD, the caspase activated deoxyribonuclease (DFF40/CAD) is released and activated and eventually causes the |
| Immunogen | Immunogen: DFF45 antibody was raised against a 20 amino acid peptide near the amino terminus of human DFF45. Buffer: DFF45 Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [DFF45; DFF1; ICAD; DFF-45; DFF1; DFF45; H13; DNA fragmentation factor subunit alpha; DNA fragmentation factor 45 kDa subunit; DNA fragmentation factor, 45kDa, alpha polypeptide], [DFFA; DFFA; DFF1; ICAD; DFF-45; DFF1; DFF45; DFF-45; ICAD] |
| Gene, Accession # | [DFFA], Gene ID: 1676, NCBI: NP_004392, UniProt: O00273 |
| Catalog # | MBS150439 |
| Price | $375 |
| Order / More Info | DFF45 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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