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Antigenic Specificity | ACE |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. Inhibitors of ACE are commonly used to treat hypertension and some types of renal and cardiac dysfunction.The glycosidase activity probably uses different active site residues than the metalloprotease activity. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-270 of human ACE (NP 690043.1). |
Other Names | [DCP; ACE1; DCP1; CD143] |
Gene, Accession # | [ACE], Gene ID: 1636, NCBI: ABA39229.1, UniProt: P12821 |
Catalog # | MBS8545070 |
Price | $280 |
Order / More Info | ACE Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |