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Antigenic Specificity | IL-34 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Interleukin-34 (IL-34) was identified through a functional screening of a library of secreted proteins after transfection of an embryonic kidney cell line with recombinant cDNAs. Flow cytometry and monocyte viability assays demonstrated increased survival and/or proliferation of monocytes induced by IL-34 and specific binding of IL-34 to CD14+ monocytes. IL-34 is a second ligand to the colony stimulating factor (CSF)-1 receptor in addition to CSF1. Like CSF1, IL-34 stimulates phosphorylation of ERK1 and ERK2 in human monocytes and induces differentiation of bone marrow cells into macrophages. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 13 amino acid peptide from near the center of human IL-34. |
Other Names | [Interleukin-34] |
Gene, Accession # | [IL-34], NCBI: ACD13474 |
Catalog # | MBS9402461 |
Price | $320 |
Order / More Info | IL-34 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |