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Antigenic Specificity | UBP1 (Center), 266-295 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This UBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-295 amino acids from the Central region of human UBP1. UBP1 functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box. |
Immunogen | n/a |
Other Names | [Upstream-binding protein 1; Transcription factor LBP-1; UBP1; LBP1] |
Gene, Accession # | [UBP1], Gene ID: 7342, NCBI: NP_001121632.1, UniProt: Q9NZI7 |
Catalog # | MBS9201829 |
Price | $165, $370 |
Order / More Info | UBP1 (Center), 266-295 Antibody from MYBIOSOURCE INC. |
Product Specific References | Katsura, A., et al. Genes Cells 14(10):1183-1196(2009) Koutnikova, H., et al. PLoS Genet. 5 (8), E1000591 (2009) : Henderson, Y.C., et al. DNA Cell Biol. 27(2):71-79(2008) Huang, N., et al. Mol. Endocrinol. 19(2):409-420(2005) Huang, N., et al. J. Biol. Chem. 275(4):2852-2858(2000) |