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Antigenic Specificity | F1A alpha |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Fas and tumor necrosis factor receptor 1 (TNFR1) are two prototype members in the death receptor family. A novel protein that associates with the intracellular domains of Fas and TNFR1 was recently identified and designated F1Aalpha and FEM1b. F1Aalpha/FEM1b is the homologue of C. elegans sex determining protein FEM-1. FEM-1/F1Aalpha is cleaved by CED-3 and caspase. FEM-1/F1Aalpha associates with CED-4 and its mammalian homologue Apaf-1. Overexpression of F1Aalpha induces apoptosis. F1Aalpha is therefore a novel member of the death receptor associated protein that mediates apoptosis. F1Aalpha is expressed in a variety of human and mouse tissues. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a peptide corresponding to amino acids 609 to 622 of human F1A alpha. This sequence is identical to the corresponding sequence of mouse FEM1b. |
Other Names | [F1A alpha] |
Gene, Accession # | [F1A alpha], NCBI: AAF05314 |
Catalog # | MBS9412594 |
Price | $320 |
Order / More Info | F1A alpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |