Edit |   |
---|---|
Antigenic Specificity | HTR1D |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity. May also play a role in regulating the release of other neurotransmitters. May play a role in vasoconstriction. |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence within amino acids 150-250 of human HTR1D (NP 000855.1). |
Other Names | [HTRL; RDC4; HT1DA; 5-HT1D; HTR1DA] |
Gene, Accession # | [HTR1D], Gene ID: 3352, NCBI: NP_000855.1, UniProt: P28221 |
Catalog # | MBS8544548 |
Price | $280 |
Order / More Info | HTR1D Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |